AI and iPSC-Neuron: Drug discovery and Safety with the MEA System

We offer research services of the MEA (micro electrode array) system leveraging human iPSC-Neuron and rodent neuron in a field of neuroscience. The MEA system has harnessed artificial intelligence (AI) analyzing numerous parameters from electric action potential of a neuron network in vitro. It can evaluate mode of toxicity (i.e. convulsion) and pharmacology of test compounds in all modality from small molecules to tissues with precise detection system and phenotypic high throughput screening. The system will support a consistent stage-up of projects covering all stages of drug discovery from initial screening through hit validation and further compound development strategy.

[contexts of use]

• Human disease model in vitro

• Phenotypic screening

• Neural pharmacology

• Epilepsy risk and mode of toxicology

• Neurodegenerative disease

• Neurotransmitter

• Axon propagation speed

• Electric footprint in a single cell

• Neural pain and hypersensitivity

• Motor neuron

• Cerebral organoid in 3D

• Extrapolation to clinical for translational research

• Alternatives to animal study