Fermentation Optimisation

Microbial conversion of sugars to chemicals and fuels is considered advantageous over chemical processes, but is a challenging area due to the high number of variables involved in the process. Fermentation process development involves: selection of microbes to produce the desired product, screening of microbes, media engineering, process optimisation, scale-up, downstream designing, etc. Screening and optimisation involve hundreds of runs which is labour and time intensive. Know-how in the area of microbiology, bioprocess engineering and design of experiments (DOE) can significantly reduce the number of experimental runs and time involved in the preliminary screening and optimisation process.

With our CIO Lalitha, our CTO Kemal, and our Bioanalysis Developer Sajna we have the expertise and knowledge to optimise fermentation processes for high yield and productivity in short-time. Our personnel have proven scientific record in producing enzymes, biofuels, biosurfactants, exopolysaccharides and prebiotics through aerobic and anaerobic fermentation processes.

Celignis also has numerous bioreactors, ranging from 1 litre to 100 litres capacity, that allow us to undertake an extensive DoE approach in optimising fermentations.

Our expertise in fermentation is particularly relevant to the following topics of the 2022 CBE-JU Work Programme: JU-CBE-2022-IA-04 (Co-processing of mixed bio-based waste streams), JU-CBE-2022-IA-02 (Cooperative business models for sustainable mobilisation And valorisation of agricultural residues, by-products, and waste in rural areas), JU-CBE-2022-IA-03 (Cost-effective production routes towards bio-based alternatives to fossil-based chemical building blocks), JU-CBE-2022-R-04 (Proteins from alternative and unconventional sources), JU-CBE-2022-IAFlag-01 (Maximum valorisation of sustainably sourced bio-based feedstock in multi-product, zero-waste, zero-pollution biorefinery), and JU-CBE-2022-IA-01 (Biogenic carbon capture and use (CCU) For circular bio-based products).