Scalable Adherent Cell Culture Technology (CellScrew®)

Green Elephant Biotech is a biotechnology start-up focused on simplifying and improving the scale-up of adherent cell processes for advanced therapies. The company addresses one of the key challenges in biomanufacturing: enabling reliable, large-scale production without forcing researchers to change their established biological workflows.

Its flagship technology, the CellScrew®, is a dynamic 2D cell culture system that allows adherent cells to be cultivated at scale while maintaining familiar culture conditions from early research through clinical and commercial manufacturing. Unlike traditional suspension systems or complex fixed-bed reactors, the CellScrew enables seamless process transfer and scalability based on proven biological principles.

The system is widely applied in viral vector production, cell and gene therapies, and other adherent cell–based bioprocesses. Designed to integrate easily into existing facilities, the CellScrew reduces manual handling, increases process robustness, and improves reproducibility.

By combining deep biological expertise with engineering-driven innovation, Green Elephant Biotech builds technology around biology rather than adapting biology to technology. Its solutions enhance manufacturing efficiency, flexibility, and reliability, supporting faster and more cost-effective delivery of advanced therapies to patients worldwide.