PI
Friedrich Schiller University Jena
Jena, Germany
Academic group leader in hematology and molecular biology, studying differentiation blockade in acute myeloid leukemia and developing laser-based single-cell technologies for transcription factor analysis.
I am a group leader in hematology and molecular biology at the University Hospital Jena, where I have been working as a principal investigator since 2015. Prior to this, I completed postdoctoral training in London, which shaped my research focus at the interface of molecular biology and translational hematology.
My research centers on the mechanisms underlying differentiation blockade in acute myeloid leukemia and on the development of differentiation-based therapeutic strategies. In parallel, I have established and continue to advance laser-based technologies for the analysis of transcription factor activity. This includes genome-wide approaches in bulk populations, such as UV ChIP-seq, as well as single-cell methods, in particular Laser-Flow Cytometry, enabling the detection of active transcription factor states at high resolution.
Ongoing work in my group focuses on further developing these technologies and applying them to clinically relevant questions, with the aim of improving disease stratification and therapeutic monitoring.
Skills
Interests
Project cooperation
We seek a postdoc for a joint MSCA Postdoctoral Fellowship application (host: University Hospital Jena, Germany) to pioneer UV laser ChIP-seq for transcription factor (TF) mapping. Basic ChIP-seq experience (wet lab + analysis) is preferred.