Project cooperationUpdated on 15 May 2026

Microbiome based Early Cancer Detection via Extracellular Vesicles

RESEARCH at Istituto Superiore di Sanità

Roma, Italy

About

Our multidisciplinary team integrates expertise in molecular oncology, extracellular vesicle (EV) biology, multi-omics analysis, and AI-driven bioinformatics, with a strong focus on translational cancer research. The group has consolidated experience in:

• Liquid biopsy technologies, particularly EV-derived biomarkers in the cancer and microbiome discovery field

• Next-generation sequencing (NGS) and targeted cancer panels

• Proteomics (RPPA) and integrative multi-omics data analysis

• Advanced in vitro tumor models, including cancer stem cell-derived spheroids to mimic tumor heterogeneity

• Development and optimization of innovative high-sensitivity detection platforms

• Implementation of AI-supported analytical pipelines for biomarker discovery and predictive modelling in cancer and microbiome

• Cooperation and Management of partners for study participants' enrollment

The team operates in a clinically oriented framework, ensuring scalability, reproducibility, and regulatory compliance (GDPR-ready data integration), with the objective of accelerating the clinical translation of non-invasive diagnostic tools.

Topic

  • HORIZON-MISS-2026-02-CANCER-02: Microbiome for early cancer prediction before the onset of disease

Organisation

Istituto Superiore di Sanità

Authority/Goverment

Rome, Italy

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