Research Director Pharmacology, Center of Clinical, Experimental Surgery & Translational Research,
Pharmacolgy Tamvakopoulos Lab
Athens, Greece
Therapeutics with a focus on cancer, specifically development/optimization of targeted therapies based on peptide conjugates or protein degraders (PROTACS).
Following his education in the United States, Dr Tamvakopoulos spent twelve years in the pharmaceutical industry in Divisions of Pharmacokinetics and Drug Metabolism working initially on Clinical Studies and subsequently in early Drug Discovery research (Merck & Co, Rahway US). In 2004 he moved to Greece at the Biomedical Research Foundation o the Academy of Athens (BRFAA), in which he is currently Research Director/Researcher A’ in Pharmacology. Dr Tamvakopoulos has more than twenty five years of Industrial/Biotechnology experience in all phases of development of therapeutics in Cancer, Metabolic disorders (obesity, diabetes), inflammation, pain and atherosclerosis.
His current research interests are in Targeted Anticancer Therapeutics and novel degraders of oncogenic proteins. His lab focuses on all aspects of Pharmacology & Pharmaceutical Technology to explore innovative therapeutic approaches with a particular focus on cancer.
His group’s research is directed towards the development and/or optimization of targeted therapies based on cytotoxic and/or antiangiogenic small molecules, peptides, or peptide conjugates or protein degraders for the treatment of solid tumors, that could become potentially promising commercial drug products in the future. In addition, the lab maintains a pertinent interest in the discovery of novel biomarkers of disease.
Additional questions
Areas od activity
Organization type
Research organizationService
LC-MS/MS based assays for the quantification of small molecules, peptides, PROTACS, in biological fluids for preclinical or clinical studies
Research Director Pharmacology, Center of Clinical, Experimental Surgery & Translational Research, at Pharmacolgy Tamvakopoulos Lab
Athens, Greece
Expertise
Consultation in drug discovery/drug development activities
Research portfolios Preclinical study consultation Due diligence evaluation for VC funds, banks, private equity
Research Director Pharmacology, Center of Clinical, Experimental Surgery & Translational Research, at Pharmacolgy Tamvakopoulos Lab
Athens, Greece
Expertise
ADVANCING PROTEIN DEGRADERS PROTACS or MOLECULAR GLUES
ADVANCING PROTEIN DEGRADERS PROTACS or MOLECULAR GLUES THROUGH THE VARIOUS STAGES OF DEVELOPMENT.
Research Director Pharmacology, Center of Clinical, Experimental Surgery & Translational Research, at Pharmacolgy Tamvakopoulos Lab
Athens, Greece
Partnership
Targeted Cancer Therapy Using Novel Biotin-Derived Platinum Analogues
Next-gen platinum compounds that enter cancer cells through SMVT, a biotin transporter highly expressed in ovarian, breast, lung tumors.
Research Director Pharmacology, Center of Clinical, Experimental Surgery & Translational Research, at Pharmacolgy Tamvakopoulos Lab
Athens, Greece