Project cooperationUpdated on 27 May 2026
Sex-specific molecular mechanisms with endothelial cells from dizygotic twin pairs
Senior Scientist at Deutsches Herzzentrum der Charité; Klinik für Kardiologie, Angiologie und Intensivmedizin, CCM
Berlin, Germany
About
We are studying sex differences at the cellular level with human endothelial cells from umbilical cords (HUVEC). Thereby, we are working with endothelial cells from dizygotic female/male twin pairs. They have the advantage that they are during pregnancy subjected to the same maternal life style and environmental factors. In addition, they share 50% of their genomes, thus further reducing inter-individual variability. These features make them especially suitable to elucidate hormone-independent sex-specific molecular mechanisms and functional pathways at the cellular level.
Topic
- DESTINATION 3: HORIZON-HLTH-2026-01-DISEASE-11: Understanding of sex and/or gender-specific mechanisms of cardiovascular diseases: determinants, risk factors and pathways
- DESTINATION 3: HORIZON-HLTH-2026-01-DISEASE-15: Scaling up innovation in cardiovascular health
Similar opportunities
Project cooperation
- Partner seeks Consortium/Coordinator
- DESTINATION 3: HORIZON-HLTH-2026-01-DISEASE-11: Understanding of sex and/or gender-specific mechanisms of cardiovascular diseases: determinants, risk factors and pathways
- DESTINATION 3: HORIZON-HLTH-2026-01-DISEASE-09: Multisectoral approach to tackle chronic non-communicable diseases: implementation research maximising collaboration and coordination with sectors and in settings beyond the healthcare system (GACD)
Seyma Aydinlik
Senior researcher at TUBITAK
KOCAELI, Türkiye
Project cooperation
Mechanisms of sexual dimorphisms in mice
- Partner seeks Consortium/Coordinator
- DESTINATION 3: HORIZON-HLTH-2026-01-DISEASE-11: Understanding of sex and/or gender-specific mechanisms of cardiovascular diseases: determinants, risk factors and pathways
Nitzan Gonen
Principal Investigator at Bar Ilan University
Ramat Gan, Israel
Project cooperation
- DESTINATION 3: HORIZON-HLTH-2026-01-DISEASE-15: Scaling up innovation in cardiovascular health
- DESTINATION 3: HORIZON-HLTH-2026-01-DISEASE-11: Understanding of sex and/or gender-specific mechanisms of cardiovascular diseases: determinants, risk factors and pathways
Cristy Verzijl
Postdoctoral researcher CardioMetabolic diseases at University Medical Center Groningen
Groningen, Netherlands