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Elena Conti

Medical Doctor, Cardiologist, MD, PhD

Pancy-BeLiver

Rome, Italy

Organisation from Academic Sector

Cardiologist. Cell & Mol Cardiology PhD30 years of activities in Cardiology & Intensive/Outpatient Cardiac Care Units. Applicant for Postdoctoral Fellowship

My organisation

Pancy-BeLiver

Pancy-BeLiver

Company (SME, Spin-off, Start-up)

Rome, Italy

Animated by a One Health– One World View, and by a pathophysiological perspective, the present Pancy small-SME is created to lead the International and Intercontinental, twofold articulated into the Pancy-BIHEART (A) to be led at the Center for International Security and Cooperation Freeman Spogli Institute, Stanford University, with Professors Stephen P. Luby and Daniel Mark Spielman, jointly with the BeLiver HEART” (B) to be led at the Sorbonne Universitè-Hopitaux Pitiè Salpetriere, with Professor Wilfried Le Goff. The small SME structure will be of the “circular type”, with the inner decisional circle constituted by the inspirer Elena Conti and the three above-mentioned Professor Stephen P. Luby, Professor Daniel Mark Spielman, and Professor Wilfried Le Goff. The structure, for the moment, will enclose only them and the other two organizational figures, who will be later detailed, for a total of 6 people. The main commitment of the SME will be to care for and effect the implementation of the two Research (Sub)Projects dedicated to newly emerging or worsening diseases, increasingly appreciated as deriving from the intertwining of communicable and non-communicable illnesses. Especially, the project rests upon the documentation of the greatly after-COVID-19 increased prevalence of hypertension and cardiovascular & metabolic outcomes, previous main research interest, jointly with IGF-1 pathophysiology, of the Pancy SME promoter, and part of the inner leaders’ circle. The neurological and the neurovascular outcomes, too, registered during Sars-CoV, Sars-CoV-2, and post-COVID-19 era, appeared to be profoundly modified by newly emergent Sars-CoV-2-coinfected Taeniasis-cysticercosis disease. New data ease the suspicion that an increased rate of cardiometabolic illnesses was induced by the crucially interplaying role of the Taenia-cysticercosis on Sars-CoV-2 disease, demanding a specific and separate diagnostic & therapeutic effort, and for deepened investigations on mitochondrial-, B vitamin- and ACE2-modifying cysticercosis effects, deeply involved in the pathogenesis of many heart-cardiovascular and brain-neurological-neurovascular diseases. The strategic vision of the microSME will be that of reconnecting worlds and peoples, across the management of this zoonotic in dynamic, but human in nature, disease, since human beings are the definitive host of Cysticercosis. The strategic mission will be that of uncompromisingly pursuing the care and the cure of the single and of the Sars-CoV-2-intertwined cysticercosis disease, ambitiously willing to establish milestones for the definition of its natural history, complications, care, and hopefully innovative cures for all the unfolded pathogenetic potential of the disease, and hopefully vaccines.   This old, better defined “ancient”, and together oddly untackled disease, in time increasingly widespread worldwide, can no longer be considered neglected. Being re-emerged as an effect of the concurrent SARS-CoV/Sars-CoV-2 pandemics, more relevant per prevalence, and of the HIV epidemic, more relevant per severity, cysticercosis currently counts, according to some, up to 11 million people affected in Europe, 12 million affected people in the United States by March 2024, and 50 million affected with larvae worldwide. A unique experience of population “snapshots”, big picture views, and of the direct and innermost understanding of infectious and preventive medicine issues at the population level is also forecasted as possibly achieved from this SME, by widening the arena of the involved countries, at the moment limited to three (Italy, France, United States). A fruitful interchange is also expected to establish between infectious disease specialists' and cardiologists' perspectives, setting an in-depth evaluation of the real bond already instituted, and even more widening among communicable and non-communicable diseases. To this, the pathophysiological arms of both to be realised at A and B subsegments by Professor Spielman and LeGoff, respectively, could become enlightening. Lastly, the importance of B1-B12 vitamin replenishment in the short-, medium-, and long-term, for care of either cardiovascular-respiratory or neurological clinical manifestations, will also be addressed.
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About me

Graduated in medicine-1994. Specialized in Cardiology-1998. PhD in Molecular and Cellular cardiology-2003, working on the subject of IGF-1 and myocardial infarction. European Accreditation in Intensive Cardiac Care-Paris-October 2008. Master’s degree in Clinical Competence in Cardiac Intensive Care-Florence University-2010. Thereafter research less than part-time, jointly with ward duties, into acute coronary syndromes and growth factors in vascular disease biology. Works and investigates in the field of diabetes, atherothrombosis, acute coronary syndromes, national and international surveys, such as- EYESHOT investigation. Focus in research-2010: role of growth factor deficiency in atherothrombosis and hypertensive disease, amyotrophic lateral sclerosis, or cancer with eye disease in patients treated with targeted drugs. Projects proposed to French industries, such as Ipsen-2011. Recent interest in Sars-Cov2-related manifestations, & related thrombotic or hypertensive risk. More work dedicated to the dramatic eminent infestation multiplier of Sars-CoV-2 affection, cysticercosis by Taenia larvae, known to medicine since decades, and outblown in two peaks in the recent fifty years, due to HIV first and Sars-CoV-2 epidemics-pandemics thereafter.

Currently job moving, due to personal and familiar health issues, now improving for what attains her health and that of her direct family, after a 30 year-long Cardiology career, following a Cardiology specialty degree (1998), and atop a Cardiology PhD in June 2003 in Cellular and Molecular Cardiology on the subject of IGF-1 in Myocardial Infarction and Cardiac Diseases, later researched on IGF-1 and Cardiometabolic diseases, for a cumulated period of less than 3 full-time years, across the time elapsed from PhD gathering until now. Beside, and principally, she gained a steady clinical foundation at Cardiology Specialty and then across around 30 years, as an assistant cardiologist, and since 2003 at the Cardiovascular and Thoracic Science and Cellular and Molecular Medicine Departments, Cardiology and Cardiac Surgery Chairs of the Faculty of Medicine and Psychology, Sapienza University of Rome up to August 2024, when she got a work leave and than a break due, - (beyond an after Covid-19- and after-cysticercosis generated multiple familiar significant health and health-related problems)–  to a personal bad polytrauma with severe long-lasting complications now improving-.

She devoted herself to funding and promoting the local Intensive Cardiac Care Unit since 2004, and kept on managing this activity until April 2016. Concurrently-accordingly, she was committed to Emergency Cardiology teaching at Cardiology Specialization, while working at the Intensive Cardiac Care Unit and Cardiology Unit, where she trained and perfected her proficiency, also applied to Emergency and Acceptance Department. She also collaborated on a National application for funding and study enrollment into Multicentric, placebo-controlled, dose-response trial awarded a national MIUR- PRIN grant, and led Primary and Secondary Cardiovascular Prevention programs at the Outpatient Cardiovascular Care Unit since April 2016. Here, she also delved into deepening knowledge on insulin resistance, diabetes, and hypertension, representing the main multiplicative risk burden determining the onset of atherothrombotic vulnerable blood and patient, and the evolution towards thrombotic and arrhythmic early, medium, and late complications.

She raised an international and intercontinental collaboration, lasting for more than 12 years, since 2010, with an outstanding South African hypertension researcher, Alta Schutte, now relocated to Australia. This partnership gave rise to several published papers on IGF-1 linking the hypertension and dysmetabolism topics, in the wake of her previous research interests. A collaboration project was signed between Italy and South Africa, and their respective Sapienza and North-West Potchefstroom Universities. The project was a branch of the global PURE study, importantly investigating insulin resistance, and thereby letting a scientific-technological cooperation begin, with an allotted grant reserved, aiming at evaluating IGF-1 axis assessment in a large (over 2000 patients) high cardiovascular risk primary prevention population study.

More recent interest in cardiovascular reverberations of SARS-CoV-2 and coinfectants has generated several insights, perspectives, and review papers, under evaluation at several high-impact Scientific Journals.

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Skills

  • Cardiology and Cardiometabolic Research
  • Phd Cellular and Molecular Cardiology
  • Master in Intensive Cardiac Care
  • ESC Accreditation in Intensive Cardiac Care
  • Interdisciplinary Diabetes-Neurological Disease
  • infectious diseases
  • Acute Intensive Cardiac Care
  • Primary and Secondary Prevention
  • Researching and Project design
  • project development
  • Data Acquisition and Analysis

Interests

  • IGF-1 in Health and Disease
  • Cardiovascular risk
  • Pathogenesis of diseases
  • Communicable Diseases
  • non communicable diseases

Marketplace (3)

  • Expertise

    Elena Conti, MD, PhD

    Cardiologist. Cell & Mol Cardiology PhD. Senior Cardiologist, Intensive/Outpatient Cardiac Care Units. Applicant for Postdoctoral Fellowship

    Author

    Elena Conti

    Medical Doctor, Cardiologist, MD, PhD at Pancy-BeLiver

    Rome, Italy

  • Expertise

    PANCY

    For managing the designed PANCY-BiHEART Translational Multicentric International Intercontinental Interdisciplinary Research Project

    • LIF - Life Sciences
    • STAFF EXCHANGES: Beneficiary / Associated Partner
    • POSTDOCTORAL FELLOWSHIPS: Hosting Postdoctoral Candidates / Secondments / Placements
    Author

    Elena Conti

    Medical Doctor, Cardiologist, MD, PhD at Pancy-BeLiver

    Rome, Italy