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Mihail Eugen Hinescu

General Manager

Victor Babes National Institute of Pathology

Bucharest, Romania

1 profile visitOrganisation from Academic Sector

Our mission is to discover molecular and cellular mechanisms involved in non-communicable diseases, using cryo-EM, CEMOVIS, CLEM, STED super-resolution .

My organisation

The Victor Babes National Institute of Pathology in Bucharest was founded in 1887 and it has been ever since a reference center for preclinical medical research in Romania. Our mission is to discover molecular and cellular mechanisms involved in various pathologies, from non-communicable diseases to tumor pathology. Our efforts are focused on identifying early diagnosis biomarkers and novel therapy targets, as precisely as possible so that patients can benefit from personalized therapies. IVB provides specialized diagnostic services for patients and research services for companies and other institutions. The Institute has modern laboratories for pathology, genetics, molecular biology, biochemistry, electron microscopy and an authorized animal facility for small rodents. Complementary techniques are available for cellular and molecular imaging at high resolution: cryo-EM, CEMOVIS, CLEM, single particle, confocal microscopy, STED super-resolution microscopy (https://www.cell-imaging.ro). Genomic analysis (ddPCR, RT-PCR, qRT-PCR, Sanger and NextGen sequencing) and multi-protein analysis technologies (xMAp array/Luminex 200 platform, protein microarray) are also available.
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About me

Victor Babeș National Institute of Pathology (www.ivb.ro) mission is to discover molecular and cellular mechanisms involved in non-communicable diseases. Our efforts are focused on identifying early diagnosis techniques as precisely as possible so that patients can benefit from personalized therapies. IVB provides specialized diagnostic services for patients and research services for companies and other institutions. IVB has modern laboratories for pathology, genetics, molecular biology, biochemistry, electron microscopy and an authorized animal facility. Complementary techniques are available for cellular and molecular imaging at high resolution: cryo-EM, CEMOVIS, CLEM, single particle, confocal microscopy, STED super-resolution microscopy (https://www.cell- imaging.ro).

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Skills

  • super-resolution microscopy
  • animal models (rodents)
  • in vitro 3D models/tumor organoids
  • cryo-electron microscopy

Interests

  • solid cancers (melanoma, glioblastoma)
  • kidney ultrapathology (electron-microscopy)
  • redox biology
  • microbiota in neurodegenerative diseases

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