Request
We are seeking a postdoctoral researcher to join our team of the Reproductive Biology and Bioengineering in Human Reproduction Reserach Line
Author
Principal Investigator at La Fe Health Research Institute
Valencia, Spain
Francisco Domínguez Hernández
Principal Investigator
La Fe Health Research Institute
Valencia, Spain
1 profile visit
Our research bridges human embryology, cell engineering, and reproductive endocrinology to advancing reproductive science through cutting-edge in vitro models.
My organisation
La Fe Health Research Institute (IIS La Fe) leads the research and innovation policy of the Health Department "Hospital La Fe". IIS La Fe promotes and develops quality translational research and health innovation, aimed at solving health challenges, increasing scientific and economic knowledge, and improving quality of life of society”. Since 2009, IIS La Fe is accredited by the Spanish Ministry of Science and Innovation as a "Health Research Institute", in recognition of the quality of its R&D and Innovation.
SCIENTIFIC AREAS: Advanced Therapies Translational Research of Prevalent Diseases and its underlying mechanisms Oncology and Oncohaematology Reproductive Medicine, Perinatology and Children’s Health Safety in the development and use of drugs New Health-applied Technologies Preventive and Sustainable Healthcare System
SCIENTIFIC MEMBERS IIS La Fe consists of 20 accredited research groups, each of which has at least 10 members including physicians, scientists and technicians, who develop a scientific strategic plan externally evaluated. Moreover, several Joint Research Units with reference research institutions are part of IIS La Fe: University of Valencia, Polytechnic University of Valencia, Principe Felipe Research Centre, and Spanish National Research Council (CSIC).
STRENGTHS: Human capital, with a staff of over 400 researchers and managers Commitment to excellence and quality managed with international regulations (GLPs, GMPs, GCPs and ISO)
About me
The Domínguez Lab, currently operating in collaboration with the Stanford School of Medicine and IVIRMA Global Alliance, is dedicated to advancing human reproductive science through the development of cutting-edge in vitro models that faithfully recapitulate early embryo implantation and endometrial receptivity. Our research bridges human embryology, cell engineering, and reproductive endocrinology to understand the dynamic interactions between the embryo and the maternal endometrium during the critical window of implantation.
We leverage advanced bioengineering platforms, including 3D endometrial scaffolds and CRISPR-derived embryonic models, to explore how chromosomal abnormalities, endocrine disruptors, and hormonal cues affect embryo development and implantation outcomes. Our novel CREST (Cell-engineered Receptive Endometrial Scaffold Technology) platform enables high-resolution analysis of trophoblast invasion, epithelial clearance, and stromal responses in both euploid and aneuploid human embryos.
With a strong foundation in translational science, our lab's mission is to generate clinically actionable insights that improve assisted reproductive technologies (ART) and IVF success rates, while also contributing fundamental knowledge on early human development.
Skills
- reproductive medicine
- Embryology
- CRISPR
- single-cell sequencing
- CREST
- Art
- IVF
- endometrium
- endocrine disruptors
- Cell Engineering
- endometrial receptivity
- organoids
Interests
- reproductive medicine
- Embryology
- CRISPR
- single-cell sequencing
- CREST
- Art
- IVF
- endometrium
- endocrine disruptors
- Cell Engineering
- endometrial receptivity
- organoids