MEIHONG XU

Assoc Prof. at the School of Public Health, Peking University. My research focuses on the role of food-derived bioactive substances (e.g., bioactive peptides, nucleotides, beta-glucans) in anti-aging and healthy aging, with a particular emphasis on nutritional interventions for age-related degenerative diseases.

Key Research Contributions

1. Anti-Aging Mechanisms of Bioactive Peptides

   • Led a study using intestinal organoid chips to demonstrate that ginseng oligopeptides inhibit excessive cell proliferation, enhance antioxidant capacity (e.g., reducing H2O2 levels), and promote mucus secretion in aged gut models, offering new insights for maintaining intestinal health in aging populations .

   • Investigated the effects of peptide-based interventions (e.g., collagen-derived peptides) on mitigating sarcopenia and neuroinflammation in animal models of Alzheimer’s and Parkinson’s diseases .

2. Nucleotides and Healthy Aging

   • Led the first-in-China human trial on nucleotide supplementation, showing significant DNAmAge slowing, telomere shortening, immune rejuvenation, and prevention of muscle atrophy in middle-aged and elderly participants .

   • Authored authoritative texts like Nucleotide Nutrition and Geriatric Nutrition, shaping academic frameworks for nucleotide research and application .

xumeihong@bjmu.edu.cn