Antibody engineering

Our proprietary SIMPLE Antibody™ platform sources V regions from the immune systems of outbred llamas, which naturally produce highly diverse antibodies with strong similarity to human antibodies. This diversity allows argenx scientists to identify antibody candidates that recognize novel and complex disease targets often missed by traditional discovery methods.

By combining llama-derived V regions with fully human Fc regions, argenx creates a library of human-like antibodies that can be tested across multiple epitopes to find the right balance of potency, safety, and species cross-reactivity. This enables a more efficient discovery process and accelerates early-stage development.