Programmable RNA Screening & Therapeutic Development for CGT and Regenerative Medicine

We propose to leverage our programmable, multiplexed RNA control platform to identify and implement optimal gene silencing strategies for therapeutic applications in cell and gene therapy and regenerative medicine. By enabling target specificity with tunable silencing levels, and independent, combinatorial control of multiple genes, our system allows systematic exploration of gene dosage and network effects to define precise therapeutic windows. This approach moves beyond binary knockdown to establish controlled gene regulation as a foundation for optimizing cellular function, differentiation, and regenerative potential. We are seeking collaborators in disease biology, CGT, and translational research to co-develop and validate next-generation RNA-based therapeutic strategies.