From Baltic Region to European Cooperation

3 – 6 Jun 2025 | Brussels, Belgium

Project cooperationUpdated on 16 May 2025

Nanoscale treatment planning for particle radiation therapy

Antoni Rucinski

Researcher at Institute of Nuclear Physics PAN

Krakow, Poland

About

Particle radiation therapy with protons and ions offers significant advantages for cancer treatment. However, a major limitation is the uncertainty in biologically weighted treatment planning, which relies on absorbed dose and relative biological effectiveness (RBE). This project aims to develop an innovative approach for particle radiation therapy using a novel nanoscale physics concept called cluster dose. This concept considers the ionization of DNA molecules at the nanoscale as the primary physical process causing DNA damage and cell inactivation due to radiation, and once applied, enables more precise treatment planning and potentially improves clinical outcomes. AI-driven models should enhance the clinical application of the cluster dose approach.

Topic

  • Cluster Health (CL1): HORIZON-HLTH-2025-01-TOOL-03: Leveraging multimodal data to advance Generative Artificial Intelligence applicability in biomedical research (GenAI4EU)

Type

  • Consortium/Coordinator seeks Partners

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