GMP Recombinant Cytokines & Growth Factors for Cell & Gene Therapy Manufacturing

Croyez Bioscience (Taiwan) supports cell and gene therapy manufacturing with a broad panel of GMP-grade recombinant proteins, including cytokines and growth factors widely used in immune cell expansion and cell therapy workflows: IL-1beta, IL-2, IL-3, IL-4, IL-6, IL-7, IL-10, IL-15, IL-18, IL-21, GM-CSF, IFN gamma, TNF alpha, TGF beta 1, Activin A, TPO, FGF-2, Flt-3 Ligand, SCF, 4-1BBL, and EGF.

Example application — Cytokine-Induced Killer (CIK) therapy: CIK cells (CD3+CD56+) combine T-cell potency with NK-like broad tumor targeting, killing tumor cells via both MHC-restricted and NKG2D-mediated, MHC-unrestricted pathways, with demonstrated efficacy across solid and hematologic cancers. CIK therapy carries low graft-versus-host risk, can be infused in outpatient settings, and is manufactured rapidly and at scale, expanding PBMCs within 2-3 weeks under GMP conditions with cells remaining stable after cryopreservation. It is combination-ready with surgery, chemotherapy, targeted agents, and checkpoint inhibitors, with growing clinical evidence — especially in hepatocellular carcinoma — pointing to reduced recurrence after treatment.

Our GMP-grade recombinant proteins are manufactured to support exactly this kind of cell expansion step, giving cell and gene therapy developers and CDMOs a reliable, scalable raw material source.

We are seeking distribution and channel partners in Europe who serve cell and gene therapy developers, CDMOs, and academic groups working on CIK, CAR-T, TIL, and other adoptive cell therapies.