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Guido Zaman

Managing Director

Oncolines B.V.

Oss, Netherlands

1 profile visitDutch mission participant Biotech

Oncolines provides drug discovery services in oncology and cancer immunotherapy. We help to bring novel therapies to the right patient population faster.

My organisation

Oncolines B.V.

Oncolines B.V.

Company

Oss, Netherlands

Oncolines B.V., a subsidiairy of Symeres Netherlands B.V., is a precision medicine services company in oncology, immunology and cancer immunotherapy. Our Clients are clinical and preclinical biopharma companies and academic institutions that seek differentiation for their drugs and drug candidates. By cancer cell panel profiling, we identify predictive drug response biomarkers, new disease indications and synergistic drug combinations. We present results in a unique interactive reporting format to facilitate easier and faster interpretation of results. To investigate the mechanism of action of compounds, we perform gene and protein expression analysis, DNA and RNA sequencing. We generate, process, analyze, visualize, and interpret complex data. We present meaningful data and discuss them with our Clients. With our extensive reference compound database we identify differentiation and mechanism of action. We share our knowledge in cancer drug development. We help cancer researchers to move their projects to the clinic faster. Oncolines B.V. was founded in 2021 as a spin-off company of Netherlands Translational Research Center B.V. (NTRC), a biotech company established in Oss (The Netherlands) in 2011 by former employees of Organon/MSD at the Pivot Park in Oss. Oncolines is named after its large cancer cell line panel (the Oncolines® panel) and its cell line proliferation assay and bioinformatics services. Oncolines was acquired by Symeres in January 2023. Symeres is a transatlantic CRO and CDMO with more than 600 employees in the Netherlands, Finland, Czech Republic and the United States.
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Marketplace (3)

  • Service

    Oncolines cancer cell panel profiling

    Oncolines profiling is the parallel testing of small molecules or biologics in a large panel of human cancer cell line viability assays.

    • Consulting
    • Development
    • Innovative therapies - Precision medicine
    • Innovative therapies - Immune cell therapy
    • Innovative human-based test models - 3D spheroids
    • Innovative human-based test models - 2D & 3D in vitro cell culture models
    • Development stages and support fuctions - Clinical research and development
    • Development stages and support fuctions - Pre-clinical research and development
    Author

    Guido Zaman

    Managing Director at Oncolines B.V.

    Oss, Netherlands

  • Service

    SynergyFinder

    Identification of novel drug combinations, either small molecules or biologics, by profiling on cancer cell lines or primary patient samples

    • Consulting
    • Development
    • Innovative therapies - Nanomedicine
    • Innovative therapies - Precision medicine
    • Innovative therapies - Immune cell therapy
    • Innovative human-based test models - 3D spheroids
    • Innovative human-based test models - 2D & 3D in vitro cell culture models
    • Development stages and support fuctions - Clinical research and development
    • Development stages and support fuctions - Pre-clinical research and development
    Author

    Guido Zaman

    Managing Director at Oncolines B.V.

    Oss, Netherlands

  • Service

    Bioinformatics

    Bioinformatic analyses based on Oncolines cancer cell panel profiling data to identify novel predictive drug response biomarkers.

    • Consulting
    • Development
    • Innovative therapies - Precision medicine
    • Innovative therapies - Immune cell therapy
    • Innovative human-based test models - 3D spheroids
    • Innovative human-based test models - 2D & 3D in vitro cell culture models
    • Development stages and support fuctions - Early discovery / basic research
    • Development stages and support fuctions - Technology development and validation
    • Development stages and support fuctions - Pre-clinical research and development
    Author

    Guido Zaman

    Managing Director at Oncolines B.V.

    Oss, Netherlands