Climate-linked Exposome Analytics Network from external to internal biological signatures affecting the brain

CLEANx2BRAIN will deliver a novel climate-to-brain-health exposome framework that is scientifically ambitious, translationally relevant, and strongly aligned with Horizon Europe's environment and health priorities. By combining dynamic exposure mapping, internal biological signatures, mechanistic validation, and explainable prediction, the project creates a credible pathway from research excellence to measurable public health and policy value. Its outputs are designed to be FAIR, reusable, and actionable for European and global brain health initiatives.