AGECARE (CYPRUS) LTD – Materia Group is a Cyprus-based healthcare, rehabilitation, and research organisation specialising in healthy ageing, geriatric medicine, clinical neuropsychology, neurodegenerative disorders, frailty, and integrated person-centred care. The organisation combines multidisciplinary clinical services with applied research, clinical trials, and the development and validation of innovative healthcare technologies.
Materia has established experience in European-funded research and innovation projects, including Horizon 2020, Active and Assisted Living (AAL), Eurostars, and European collaborative healthcare initiatives. Its Research and Development Department focuses on translational research, neurodegeneration, dementia and Alzheimer's disease, mild cognitive impairment (MCI), cognitive reserve, cognitive frailty, sarcopenia, multimorbidity, functional decline, and ageing-related conditions.
Materia has experience in the design, implementation, and evaluation of clinical research protocols, including randomised controlled trials (RCTs), pragmatic RCTs, case-control studies, longitudinal observational studies, feasibility studies, and real-world pilot interventions. Its clinical and research teams contribute to participant recruitment, eligibility screening, informed consent, clinical assessments, intervention delivery, longitudinal follow-up, outcome monitoring, data collection, and statistical evaluation.
Materia's research activities also encompass biological sample collection, biomarker assessment, and the integration of biological, neuropsychological, clinical, functional, and digital measurements. Previous research activities have included telomere-length analysis as a marker of cellular ageing, alongside the collection of biological and clinical indicators relevant to ageing and health outcomes.
The organisation is particularly interested in multidimensional biomarker approaches combining molecular and cellular ageing indicators, neurocognitive assessments, physical performance measures, frailty indices, and digital phenotyping to investigate biological ageing, neurodegenerative processes, early risk stratification, and responses to preventive or therapeutic interventions.
Materia has experience in technology-enabled healthcare interventions, including cognitive-motor training, exergaming, telerehabilitation, wearable sensing technologies, remote patient monitoring, assistive robotics, augmented and virtual reality (AR/VR), and personalised digital therapeutics. Research priorities include early detection of cognitive decline, non-pharmacological interventions, multimodal prevention strategies, functional rehabilitation, and technology-supported independent living.
The organisation contributes to clinical validation, intervention feasibility, usability and acceptability studies, patient-reported outcome measures (PROMs), functional outcome assessments, health-related quality of life, implementation research, and real-world evidence generation.
Materia is interested in participating as a clinical research, intervention, pilot-site, and end-user validation partner in interdisciplinary projects involving:
- Neurodegenerative diseases, dementia prevention, MCI, cognitive impairment, and brain health.
- Biological ageing, cellular senescence, telomere dynamics, and ageing-associated biomarkers.
- Biomarker-driven risk stratification, precision prevention, and personalised healthcare.
- Randomised controlled trials, longitudinal cohort studies, intervention efficacy, and real-world clinical validation.
- Multidomain non-pharmacological interventions targeting cognition, physical function, frailty, and resilience.
- Digital biomarkers, wearable sensors, AI-supported monitoring, digital phenotyping, and remote assessments.
- Translational geroscience, healthy longevity, integrated care, and implementation science.
Materia offers access to relevant clinical and community-based populations, multidisciplinary healthcare expertise, established research infrastructure, and experience in ethics, end-user engagement, clinical outcome assessment, and evaluation of innovative interventions in real-world care environments.