Updated on 20 October 2026
Sex-specific molecular mechanisms with endothelial cells from dizygotic twin pairs
Senior Scientist at Deutsches Herzzentrum der Charité; Klinik für Kardiologie, Angiologie und Intensivmedizin, CCM
Berlin, Germany
About
We are studying sex differences at the cellular level with human endothelial cells from umbilical cords (HUVEC). Thereby, we are working with endothelial cells from dizygotic female/male twin pairs. They have the advantage that they are during pregnancy subjected to the same maternal life style and environmental factors. In addition, they share 50% of their genomes, thus further reducing inter-individual variability. These features make them especially suitable to elucidate hormone-independent sex-specific molecular mechanisms and functional pathways at the cellular level.
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Project cooperation
Seyma Aydinlik
Senior researcher at TUBITAK UME
KOCAELI, Türkiye
Project cooperation
iPSC-derived cell therapy for COPD and IPF: experimental partners for EIC Pathfinder Open
- Consortium/Coordinator seeks Partners
Yan Ostrovski
Co-founder & CEO at Neshima Medical Ltd
Dimona, Israel
Project cooperation
Research partner with responsibility for a defined experimental task
- Destination 5: HORIZON-HLTH-2027-03-TOOL-02: Advancing bio-printing of living cells for regenerative medicine
- Destination 3: HORIZON-HLTH-2027-02-DISEASE-01-two-stage: Innovative healthcare interventions for non-communicable diseases
- Destination 5: HORIZON-HLTH-2027-03-TOOL-08: Towards the next generation of frontier Artificial Intelligence models for healthcare
- Destination 5: HORIZON-HLTH-2027-03-TOOL-04: Virtual Human Twins (VHTs) for integrated clinical decision support in prevention and diagnosis
- Destination 4: HORIZON-HLTH-2027-01-CARE-02: Personalised approaches to reduce risks from Adverse Drug Reactions due to administration of multiple medications
- Destination 5: HORIZON-HLTH-2027-02-TOOL-01-two-stage: Development of predictive biomarkers of disease progression and treatment response by using AI methodologies for chronic non-communicable diseases
Mirel Adrian Popa
Scientific Researcher at Instititute of Cellular Biology and Pathology Nicoale Simionescu
Bucharest, Romania