Clinical Trials in Luxembourg and the Grand Region Est, BioBanking for Europe

Accelerating translational medicine from concept to compliant execution 

The Luxembourg Institute of Health (LIH) provides an integrated, end-to-end framework for clinical trials and epidemiological research. Combining Good Clinical Practice (GCP) certified clinical operations, centralized project management, and state-of-the-art data and sample workflows, we help biopharma, biotech, and academic partners navigate complex health environments to bring innovative therapies to patients.  

Why partner with LIH for clinical trials & research? 

• Integrated single point of contact: Streamlined coordination through a dedicated Clinical Project Management Office (CPMO) handling contracts, timelines, budgets, and cross-functional execution.  

• GCP & regulatory excellence: Fully compliant operations (ICH-GCP, ISO, GDPR) guaranteeing patient rights, data privacy, and seamless ethics/competent authority submissions.  

• Patient-centric infrastructure: Direct access to clinical trial facilities, study nurses, clinical research associates and clinicians, and diverse patient cohorts via the Luxembourg Research Clinic (LRC).  

• End-to-end methodological rigor: Tailored trial designs, adaptive master protocols, and robust sample size calculations designed by expert biostatisticians.

Explore our core capabilities 

Proactive governance, portfolio management & single entry point 

End-to-end management of complex clinical projects. From initial feasibility and risk assessment to budget control, regulatory setup, and multi-centre monitoring via enterprise tools (Planisware Orchestra).  

GCP conform clinical operations, on-site clinical teams & patient access 

Full-scale clinical study execution at site level across Luxembourg and the Greater Region. Dedicated Research Nurses, Clinical Research Associates (CRAs), consultation rooms, and recruitment pathways to run Phase I–IV trials and observational cohorts.  

Harmonized biological sample workflows & ISO20387-accredited biobanking 

Seamless collaboration with the Integrated BioBank of Luxembourg (IBBL). From trial-specific collection kit manufacturing and site logistics to ISO accredited processing, characterization, and long-term multi-temperature storage, ensuring complete sample chain-of-custody. 

Competent authority approvals, ethics submissions & compliance 

Expert guidance through national and international regulatory landscapes. Complete preparation and submission of dossiers to Ethics Committees  and Health Authorities.  

Adaptive trial architectures, power calculations & simulation analyses 

Rigorously designed clinical research frameworks. Expert clinical trial design (single and parallel arms, adaptive, basket, platform), power calculations, and regulatory-grade Statistical Analysis Plans (SAP).  

Data curation, statistical analysis & high-impact output 

Seamless transformation of raw clinical data into regulatory-ready datasets and reports, ICH clinical report-grade TLFs, publication-grade figures, and actionable health evidence.  

Our Impact in Numbers 

• 210+ Clinical studies run / supported  

• 60+ Active sponsor collaborations (pharma, biotech, academic)  

• 10,350+ Study participants enrolled

• 96 Active managed translational projects