Cuffless Blood Pressure Monitoring with Wearable Ultrasound

We are interested in developing a new generation of wearable ultrasound systems for continuous, cuffless blood pressure monitoring.

Unlike optical or purely pulse-transit-time-based approaches, ultrasound can directly observe arterial mechanics, including vessel diameter or cross-sectional area, wall motion, pulse-wave propagation and potentially blood-flow dynamics. Combining these complementary measurements could enable more physiologically grounded BP estimation and reduce dependence on subject-specific calibration.

Our contribution would focus on wearable ultrasound electronics, low-power acquisition, embedded signal processing and edge AI, building on existing wireless wearable ultrasound platforms ranging from ultra-low-power sensing systems to higher-performance multi-channel probes.

We are particularly interested in projects addressing:

• continuous and ambulatory BP monitoring

• arterial area/distension and local vascular mechanics

• local or multi-site pulse-wave velocity

• calibration-light or calibration-free BP estimation

• multimodal fusion with ECG, PPG or other cardiovascular signals

• embedded processing and real-time inference on wearable hardware

• clinical validation against established BP reference methods

We are looking for partners with expertise in clinical cardiovascular research, ultrasound transducers, biomechanics/hemodynamics, signal processing, AI, and medical-device validation, with the goal of moving wearable ultrasound from laboratory demonstrations toward clinically meaningful continuous BP monitoring.

Selected Examples of Our Work:

- WULPUS: ultra-low-power wearable ultrasound system, demonstrating continuous sensing under stringent power budgets (https://github.com/pulp-bio/wulpus)

- TinyProbe, wearable multimodal ultrasound (A/B/M/Doppler mode), wireless and battery operated (https://ieeexplore.ieee.org/abstract/document/10750870)

- combined ultrasound and optoacoustics (https://onlinelibrary.wiley.com/doi/full/10.1002/lpor.202501006)