Project partners needed

Opportunity: Digital Health & Biomarker Innovation for Sepsis Recovery

The Challenge
Sepsis recovery is a major clinical and health-economic challenge. Diverse causes, patient demographics, and outcomes make it difficult to identify which interventions truly benefit patients—especially after discharge.

Our Expertise
At VTT, we specialize in:

• Patient health analytics

• Wearable biosensors and scalable production

• Immunoassay development

We partner with CSEM (Switzerland), leaders in:

• Wearable health monitoring

• Data acquisition and analytics

• Next-generation biosampling using microneedles

We are looking for partners:

• Clinical partners (ICU to home care)

• Rehabilitation and psychological recovery specialists

• Developers of micro-scale blood sampling technologies

• -omics experts (genomics, transcriptomics, metabolomics)

• Biobanks with relevant patient/control material

Our Solution
A digital platform enabling continuous or periodic monitoring of physiological parameters at home using low-cost/disposable wearables. Data available to clinician to help in early interventions. Complementary features include:

• Periodic biomarker analysis from blood (clinic, visiting nurse, or microvolume/dried blood spot sampling)

• Digitalized patient-reported outcomes (recovery, cognitive status)
  The platform can be standalone or integrated into national telehealth programs, serving as a recovery aid and remote monitoring solution.

Project Outline
Retrospective Study:

• Validate a minimal set of immunological biomarkers for monitoring

• Assess feasibility of measuring biomarkers from nonstandard samples

• Identify physiological readouts that support recovery and train analytics algorithms for patient stratification

Prospective Study:

• Collect data and samples from sepsis patients for up to 6 months post-onset

• Evaluate feasibility of self-monitoring with wearables

• Assess assisted/self-acquisition of blood samples

• Analyze patient-specific trends in physiological and immunological markers to guide recovery and interventions

• Refine data analytics for predictive insights