Multiscale Biofabrication and Stem Cell-Based Human Tissue Models for Regenerative Medicine and Disease Modeling

As a multidisciplinary scientist in the field of regenerative medicine and biofabrication, I bring deep expertise in the design and engineering of 3D in vitro human tissue models using a range of scalable and tunable fabrication strategies. My research spans:

• Electrospun nanofibers, melt electrowriting (MEW), and hydrogel-based bioinks to mimic the physical and biochemical microenvironment of native tissues.

• Stem-cell driven tissue formation, including spheroids and hybrid-spheroids incorporating ECM-like fragments or functionalized fibers.

• Vascularized bone, tendon-bone insertion, glomerular filtration barrier, and 3D adipose models, with applications in disease modeling, drug screening, and regenerative repair.

• Biochemical surface engineering using polydopamine, growth factor immobilization, and mussel-inspired coatings to modulate cell behavior.

• Dynamic culture platforms, including perfusion bioreactors, mechanically stimulated systems, and thermoresponsive hydrogels for spatially controlled tissue assembly.

With over 40 peer-reviewed publications in Biomaterials, Acta Biomaterialia, Advanced Healthcare Materials, ACS Applied Materials & Interfaces, and Biofabrication, I contribute to translational strategies connecting material design with biological function.

This Expertise is Offered For (Areas/Calls):

• Horizon Europe Pillar II: Health (Regenerative medicine, personalized models, biomaterials)

• DFG Collaborative Research Grants

• MSCA Doctoral/Postdoctoral Fellowships (Innovative training in bioengineering, stem cells)

• German Federal Ministry of Education and Research (BMBF) joint calls on 3D cell models

• Industry-academic co-development for drug screening, biomaterial testing, and bioink translation