European Framework for Digital NAMs in Precision Mental Health

This proposal focuses on accelerating adoption of digital NAMs across Europe by standardising Digital Twin–based methodologies for mental health research. Mential contributes the technical and clinical backbone to operationalise these NAMs at scale.

Key actions include:

• Creating shared taxonomies of digital mental health markers (FHIR-based).

• Developing best practices for reproducible digital phenotyping studies.

• Training researchers and institutions on digital NAM implementation.

• Connecting academic, clinical and regulatory stakeholders.

Mential is distinct because it already operates a production-grade Digital Twin system, not a theoretical framework. This allows immediate testing, replication and cross-country collaboration using real patient data under clinical governance.