Form & Formulation

At Sygnature Discovery, we specialize in solving the formulation barriers that stand between your molecule and successful clinical development.

Our technology-agnostic approach, grounded in expert solid-state characterization and data-driven decision-making, ensures every strategy is tailored to your compound’s properties and goals.

We seamlessly integrate solid form understanding into formulation design, aligning early decisions with downstream CMC expectations to reduce risk and accelerate your path to clinic. Whether you’re aiming for dose linearity in preclinical toxicology, improving crystallinity or solubility, or identifying the most stable polymorph to support manufacturability, our team brings the right expertise at the right time.

Working collaboratively across Process Chemistry and Scale-Up, DMPK, and Separation Science, we apply multidisciplinary insight to solve complex challenges and deliver robust, scalable solutions. Every decision is made with clarity, precision, and a shared commitment to scientific success.

• Early Clinical Formulation

• Solid Form Analysis

• Salt and Co-Crystal Screening

• Polymorph Screening

• Pre-Clinical Formulation