Manufacturing of vaccines, gene therapies & advanced therapy medicinal products

Vaccines, viral-based gene therapy products and other bionanoparticles, including virus-like particles and extracellular vesicles, pose unique challenges in bioprocessing due to their structural complexity, sensitivity to process conditions, and stringent regulatory requirements. Efficient upstream and downstream processing strategies are essential to ensure product quality, safety, and scalability while meeting growing clinical and commercial demand. We discuss recent advances in the production, purification, formulation, and quality control of vaccines, gene therapies and other bionanoparticles, when addressing both established platforms and emerging modalities. Expect a spotlight on innovative technologies that enable robust, scalable, and flexible manufacturing solutions.