Integrating New Approach Methodologies (NAMs) to advance biomedical research and regulatory testing

Venus Roses can contribute in the use cases from the nutraceutical/cosmetic domain – for example, helping to develop an in vitro skin model to test herbal cosmetic ingredients (drawing on its cosmeceutical expertise). VR’s regulatory team would collaborate with authorities to ensure these NAMs are accepted for safety assessments, effectively bridging science and regulation. Additionally, VR could implement an in silico toxicology platform for predicting the safety of new plant compounds, sharing data from its compound libraries. In the project, VR might lead a work package on demonstration, where it applies the consortium’s NAM toolbox to real products it’s developing. By doing so, VR helps prove the validity of NAMs in a regulatory context – for instance, showing that organoid or computer models can reliably replace an animal study for a supplement’s safety testing. This both benefits the project and enhances VR’s own R&D pipeline by making it more ethical and efficient.