Measurement, De-implementation, and Economic Evaluation of Low-Value Care

Arizona State University (ASU), through its Safety Net Advancement Center (SNAC), is seeking to join or help shape a consortium responding to HORIZON-HLTH-2026-01-CARE-03: Identifying and Addressing Low-Value Care in Health and Care Systems.

ASU/SNAC brings strong expertise in measurement, de-implementation, and economic evaluation of low-value care, with a focus on real-world feasibility, equity, and policy relevance. Our proposed contribution centers on developing and validating indicators of overuse, misuse, underuse, and unwarranted variation; designing and testing de-implementation strategies that maintain quality and patient safety; and evaluating economic impact and resource reallocation toward higher-value care.

We propose to lead or co-lead a work package focused on:

• Evidence-based measurement of low-value care using routine data

• De-implementation research and system redesign strategies

• Economic and ROI evaluation aligned with sustainability goals

• Mixed-methods assessment of effectiveness, equity, scalability, and transferability

• Policy-relevant dissemination and cross-country learning

ASU is a U.S. R1 public research university and a non-EU associated partner eligible for EU funding, offering complementary international perspectives, access to large-scale U.S. health system and population-level data, and experience evaluating payment and incentive models relevant to low-value care.

We are particularly interested in collaborating with EU health systems, provider networks, HTA and policy partners, patient and citizen organizations, and widening-country partners. A full project cooperation brief is attached.