Real-World Evidence and Clinical Research on Climate Change Impacts on Health

Keralty is an international integrated health group delivering care to 9 million patients with 27,000 professionals across Colombia, Peru, Mexico (LMIC), and the United States, with a strong focus on primary care, prevention, community health, and social care. Keralty has prior experience in H2020 and Horizon Europe projects, contributing real-world healthcare settings, structured cohorts, and implementation capacity.

Keralty is well positioned to contribute to HORIZON-HLTH-2026-01-ENVHLTH-01, supporting improved understanding, anticipation, and prevention of the health impacts of climate change. The organisation can contribute through:

• Access to large, diverse populations, including vulnerable and climate-exposed groups

• Experience in non-communicable diseases, multimorbidity, and climate-sensitive health conditions

• Capacity to conduct longitudinal and clinical studies, integrating health, exposure, and socio-environmental data

• Generation of real-world evidence to inform prevention strategies, resilience building, and evidence-based policymaking

Through its healthcare centres and community-based programmes, Keralty can support research on causal pathways between climatic stressors and health outcomes, as well as the identification of protective factors and resilience mechanisms at individual, community, and system levels. Keralty’s presence across different geographical and socio-economic contexts enables comparative analyses and enhances the scalability and transferability of research outcomes, including contributions aligned with One Health approaches.

In addition, BioKeralty Research Institute, part of Keralty Group’s R&D&I division, can act as a complementary research partner. BioKeralty brings expertise in digital health, personalised medicine, chronic diseases, community and social care, and contributes to the development of methodological frameworks, data analysis, and impact assessment. BioKeralty also has strong capabilities in communication, dissemination, and exploitation of results, supporting science–policy links and alignment with European initiatives such as the European Climate and Health Observatory.