Multifunctional Nanoparticles for Next-Generation Point-of-Care Devices: Magnetic, Optical, and Electro-Tagging Solutions

Our research group at CNRS (Montpellier, France) specializes in the design and synthesis of multifunctional nanoparticles tailored for point-of-care (PoC) diagnostic devices. Our expertise includes the development of nanoparticles with magnetic, optical, and electro-tagging properties, which can be engineered to enhance sensitivity and efficiency for rapid and accurate diagnostics.

We focus on:

• Cluster formation of nanoparticles to amplify signals and improve detection limits.

• Coating strategies using inorganic, organic, or polymeric shells to enhance stability in biological environments and facilitate key-lock recognition (e.g., antibody-antigen, DNA hybridization).

• Functionalization techniques to tailor nanoparticles for specific biomarkers or analytes, enabling precise and selective detection.

• Stability studies in relevant biological media to ensure reliability in real-world PoC applications.

Our group has extensive experience in European collaborative projects and is seeking partners to explore the integration of these nanoparticles into novel PoC devices for applications in infectious disease diagnostics, cancer detection, or chronic disease monitoring.

Role in the Consortium:

• Development of customized nanoparticles (magnetic, optical, electro-tagging) optimized for PoC applications.

• Functionalization and coating of nanoparticles to enhance stability and specificity.

• Characterization of nanoparticle clusters for improved sensitivity and efficiency.

• Collaboration on device integration to ensure compatibility with PoC platforms.

Type of Partners Sought:

We are looking for European partners (academic or clinical) with complementary expertise in:

• PoC device development: To integrate our nanoparticles into functional diagnostic platforms.

• Clinical validation: To test and validate our nanoparticles in real-world diagnostic settings.

• Biomarker discovery: To identify target analytes for functionalization and detection.

• Regulatory and standardization experts: To ensure compliance with medical device regulations.

• European project coordinators: To build a consortium under Horizon Europe calls, particularly in Cluster 1: Health, focusing on diagnostic innovations and personalized medicine.