Chiome Bioscience Inc.
About
Chiome Bioscience Inc. is clinical-stage antibody drug discovery biotech company with cutting edge antibody generating technology called ADLib system. Chiome is listed on TSE, growth market.
Chiome has three (3) business segments:
1 Drug discovery support
Chiome offers customer-friendly services for antibody discovery and affinity maturation utilizing ADLib® system as well as protein expression service, which are tailored to the requirements of pharmaceutical companies, IVD companies, biotechs, and academic institutions.
2 Drug discovery and development
Chiome discovers and develops novel antibody therapeutics.
CBA-1205 and CBA-1535 are in phase 1 stage in the pipeline.
”CBA-1205” :
A first-in-class antibody drug candidate targeting the DLK-1 tumor antigen with .enhanced antibody-dependent cell-mediated cytotoxicity (ADCC). Clinical studies for hepatocellular carcinoma and melanoma are ongoing.
"CBA-1535":
Trispecific antibody (Tribody) targeting 5T4 tumor antigen and CD3. Dose-escalating study is ongoing for solid tumors for this T-cell engager.
3 Integrated drug discovery (IDD)
Chiome offers comprehensive solutions for various R&D needs of partner companies on antibody therapeutics, based on our experience. IDD solutions include seamless, end-to-end support from antibody generation to preclinical and clinical development, encompassing efficacy evaluation, CMC, and study design.
Recently, Chiome has also developed a novel screening system for bispecific antibodies ("DoppeLib"). In DoppeLib, each cell display a single bispecific antibody on the surface and also secret the same bispecific antibody in the supernatant. DoppeLib enables high throughput screening of bispecific antibodies. In this opportunity, Chiome will seek a partner(s) for R&D of bispecific antibodies.
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Additional questions
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