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Chiome Bioscience Inc.

Company (SME/startup) / 中小企業・スタートアップ

www.chiome.co.jp/?id=enTokyo, Japan
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About

Chiome Bioscience Inc. is clinical-stage antibody drug discovery biotech company with cutting edge antibody generating technology called ADLib system. Chiome is listed on TSE, growth market.

Chiome has three (3) business segments:

1 Drug discovery support

Chiome offers customer-friendly services for antibody discovery and affinity maturation utilizing ADLib® system as well as protein expression service, which are tailored to the requirements of pharmaceutical companies, IVD companies, biotechs, and academic institutions.

2 Drug discovery and development

Chiome discovers and develops novel antibody therapeutics.

CBA-1205 and CBA-1535 are in phase 1 stage in the pipeline.

”CBA-1205” :

A first-in-class antibody drug candidate targeting the DLK-1 tumor antigen with .enhanced antibody-dependent cell-mediated cytotoxicity (ADCC). Clinical studies for hepatocellular carcinoma and melanoma are ongoing. 

"CBA-1535":

Trispecific antibody (Tribody) targeting 5T4 tumor antigen and CD3. Dose-escalating study is ongoing for solid tumors for this T-cell engager.

3 Integrated drug discovery (IDD)

Chiome offers comprehensive solutions for various R&D needs of partner companies on antibody therapeutics, based on our experience. IDD solutions include seamless, end-to-end support from antibody generation to preclinical and clinical development, encompassing efficacy evaluation, CMC, and study design.

Recently, Chiome has also developed a novel screening system for bispecific antibodies ("DoppeLib"). In DoppeLib, each cell display a single bispecific antibody on the surface and also secret the same bispecific antibody in the supernatant. DoppeLib enables high throughput screening of bispecific antibodies. In this opportunity, Chiome will seek a partner(s) for R&D of bispecific antibodies.

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Business Domain / 分野

Pharmaceuticals / 医薬品

Business Type / 業種

R&D / 研究開発

Disease Area / 疾患領域

Oncology / がんInfectious diseases / 感染症Immunology / 免疫・炎症Rare diseases / 希少疾患

Modalities / モダリティ

Antibody drug / 抗体医薬

Additional questions

Researched company/organisation type / マッチングご希望企業・機関のタイプ

Companies and Academia etc. (Joint research and development purpose) / 企業やアカデミア等(共同での研究、開発を目的)Major pharma etc. (Out-licensing purpose) / 大手ファーマ等(アウトライセンスを目的)

Researched disease area / マッチングご希望の疾患領域

Oncology / がんInfectious diseases / 感染症Immunology / 免疫・炎症Rare diseases / 希少疾患

Researched Modality / マッチングご希望のモダリティ

Peptide, Protein / ペプチド、タンパクAntibody drug / 抗体医薬Vaccine / ワクチン

Researched Technologies / マッチングご希望の技術

Others /その他